Iodine ACS reagent, ≥99.8%, solid
Iodine
ACS reagent, ≥99.8%, solid
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CAS Number 7553-56-2
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Empirical Formula (Hill Notation) I2
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Molecular Weight 253.81
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Beilstein/REAXYS Number 3587194
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EC Number 231-442-4
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MDL number MFCD00011355
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eCl@ss 38050601
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PubChem Substance ID 329752021
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NACRES NA.21
Properties
| Related Categories | C-X Bond Formation (Halogen), Chemical Synthesis, Iodination, Synthetic Reagents |
| Quality Level | 200 |
| grade | ACS reagent |
| vapor density | 9 (vs air) |
| vapor pressure | 0.31 mmHg ( 25 °C) |
| 1 mmHg ( 38.7 °C) | |
| InChI Key | PNDPGZBMCMUPRI-UHFFFAOYSA
|
| assay | ≥99.8% |
| form | solid |
| resistivity | 1.3E15 μΩ-cm |
| impurities | ≤0.01% nonvolatiles |
| bp | 184 °C (lit.) |
| mp | 113 °C (lit.) |
| anion traces | Cl- and Br-: ≤0.005% |
Description
General description
Iodine exhibits exceptionally high dielectric polarization in various solvents (dioxane, isobutylene, p-xylene and benzene).[3]
Application
Catalyst for synthesis of esters by condensation of carboxylic acids with alcohols or transfesterification.
A mild and efficient method for esterification and transesterification catalyzed by iodine
Iodine has been used for the easy visualization of 9-bromononanoic acid, allyl ester by thin layer chromatography (TLC).[1] It has also been used for the preparation of oxidation solution, required for the synthesis of oligodeoxynucleotides bearing 3′-terminal phosphorothioate.[2]
Iodine may be used to catalyze:
• Synthesis of 5-(4-nitrophenyl)-10,15,2
• Oxidative C-H bond amination of saturated hydrocarbons.[5]
• Protection of amines with benzyloxycarbonyl (Cbz) group.[6]
• Direct oxidative coupling/annulation of β-keto esters or 2-pyridinyl-β-esters with alkenes to form dihydrofurans and indolizine, respectively.[7]
• Thiocyanation of aromatic systems to form aryl thiocyanates.[8]
• Esterification of cellulose with acetic anhydride to form cellulose triacetate.[9]
Packaging
1, 2.5 kg in glass bottle
12 kg in steel drum
5, 100, 4×100, 500 g in glass bottle
