MERCK 100981 Benzyl alcohol suitable for use as excipient EMPROVE

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Stok Kodu
100981.6025
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Description
Catalogue Number 100981
Synonyms Phenylcarbinol
Product Information
CAS number 100-51-6
EC index number 603-057-00-5
EC number 202-859-9
Grade Ph Eur,BP,JP,NF
Hill Formula C₇H₈O
Chemical formula C₆H₅CH₂OH
Molar Mass 108.14 g/mol
HS Code 2906 21 00
Structure formula Image
Physicochemical Information
Boiling point 205 °C (1013 hPa)
Density 1.05 g/cm3 (20 °C)
Explosion limit 1.3 - 13 %(V)
Flash point 101 °C DIN 51758
Ignition temperature 435 °C DIN 51794
Melting Point -15.3 °C
Vapor pressure 0.07 hPa (20 °C)
Solubility 40 g/l
Toxicological Information
LD 50 oral LD50 Rat 1620 mg/kg
Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s) H302 + H332: Harmful if swallowed or if inhaled.
H319: Causes serious eye irritation.
Precautionary Statement(s) P271: Use only outdoors or in a well-ventilated area.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
RTECS DN3150000
Storage class 10 - 13 Other liquids and solids
WGK WGK 1 slightly water endangering
Disposal 3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Hazard Symbols Harmful
Categories of danger harmful
R Phrase R 20/22
Harmful by inhalation and if swallowed.
S Phrase S 26
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Storage and Shipping Information
Storage Store at +2°C to +25°C.
Specifications
Assay (GC) 98.0 - 100.5 %
Identity (IR) conforms
Appearance of solution (nephelometric) conforms
Clarity of solution conforms
Colour of solution conforms
Acidity conforms
Refractive index (n 20/D) 1.538 - 1.541
Density (d 20 °C/20 °C) 1.043 - 1.049
Peroxide value ≤ 5.0
Related substances (GC) (Benzaldehyde (Impurity A)) ≤ 0.15 %
Related substances (GC) (Cyclohexylmethanol (Impurity B)) ≤ 0.10 %
Related substances (GC) (Sum of peaks with a relative retention less than that of benzyl alcohol) ≤ 0.04 %
Related substances (GC) (Sum of peaks with a relative retention greater than that of benzyl alcohol) ≤ 0.3 %
Related substances (GC) (disregard limit) ≤ 0.0001 %
Benzene (GC) ≤ 0.0002 %
Chlorobenzene (GC) ≤ 0.01 %
Toluene (GC) ≤ 0.01 %
Other residual solvents (ICH Q3C) excluded by manufacturing process
Evaporation residue ≤ 0.050 %
Water ≤ 0.10 %
Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000 are not likely to be present.
Conforms to Ph Eur, BP, JP, NF
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MERCK 100981 Benzyl alcohol suitable for use as excipient EMPROVE

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