MERCK 104090 Glutathione (reduced) suitable for biopharmaceutical production EMPROVE bio Ph Eur

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Stok Kodu
104090.0005
Kategori
Havale
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0,00 TL KDV DAHİL
TEKLİF İSTE
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Description
Catalogue Number 104090
Synonyms γ-L-Glutamyl-L-cysteinglycine, GSH
Product Information
CAS number 70-18-8
EC number 200-725-4
Grade Ph Eur
Hill Formula C₁₀H₁₇N₃O₆S
Molar Mass 307.32 g/mol
HS Code 2930 90 98
Structure formula Image
Physicochemical Information
Melting Point 185 - 195 °C
pH value 3 (10 g/l, H₂O, 20 °C)
Bulk density 160 kg/m3
Solubility 100 g/l
Safety Information according to GHS
RTECS MC0556000
Storage class 10 - 13 Other liquids and solids
WGK WGK 2 water endangering
Disposal 3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Storage and Shipping Information
Storage Store at +2°C to +8°C.
Transport Information
Declaration (railroad and road) ADR, RID Kein Gefahrgut
Declaration (transport by air) IATA-DGR No Dangerous Good
Declaration (transport by sea) IMDG-Code No Dangerous Good
Specifications
Assay (iodometric, calc. on dried substance) 98.0 - 101.0 %
Identity (IR-spectrum) passes test
Appearance white to almost white, slightly agglomerated, crystalline powder
Appearance of solution (100 g/l, water) clear and colorless.
Spec. rotation (α 20/D, 40 g/l, water, calc. on dried substance) -15.5° to -17.5°
Chloride (Cl) ≤ 200 ppm
Sulphate (SO₄) ≤ 300 ppm
Heavy metals (as Pb) ≤ 10 ppm
As (Arsenic) ≤ 2 ppm
Fe (Iron) ≤ 10 ppm
NH₄ (Ammonium) ≤ 200 ppm
Related substances (CE) (Impurity A (Cysteinylglycine)) ≤ 0.5 %
Related substances (CE) (Impurity B (Cysteine)) ≤ 0.5 %
Related substances (CE) (Impurity C (Glutathione oxidized)) ≤ 1.5 %
Related substances (CE) (Impurity D (Glutamylcysteine)) ≤ 1.0 %
Related substances (CE) (Impurity E) ≤ 0.5 %
Related substances (CE) (Largest unspecified impurity) ≤ 0.2 %
Related substances (CE) (Sum of all impurities) ≤ 2.5 %
Acetic acid (HS-GC) ≤ 5000 ppm
Ethanol (HS-GC) ≤ 5000 ppm
Ethyl acetate (HS-GC) ≤ 5000 ppm
Other residual solvents (ICH Q3C) passes test
Sulfated ash (600 °C) ≤ 0.1 %
Loss on drying (105 °C; 3 h) ≤ 0.5 %
Residues of metal catalysts or metal reagents acc. to EMEA/CHMP/SWP/4446/2000
are not likely to be present.
Corresponds to Ph. Eur.
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MERCK 104090 Glutathione (reduced) suitable for biopharmaceutical production EMPROVE bio Ph Eur

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