MERCK 106432 tri-Sodium citrate dihydrate cryst., EMPROVE® ESSENTIAL Ph Eur,BP,JP,USP,E 331

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Stok Kodu
106432.5000
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Description
Catalogue Number 106432
Synonyms Trisodium Citrate, Sodium Citrate, Dihydrate
Product Information
CAS number 6132-04-3
EC number 200-675-3
Grade Ph Eur,BP,JP,USP,E 331
Hill Formula C₆H₅Na₃O₇ * 2 H₂O
Molar Mass 294.10 g/mol
HS Code 2918 15 00
Structure formula Image
Physicochemical Information
Melting Point 150 °C (anhydrous substance)
pH value 7.5 - 9.0 (50 g/l, H₂O, 25 °C)
Bulk density 600 kg/m3
Solubility 720 g/l
Toxicological Information
LD 50 oral LD50 Rat > 8000 mg/kg
Safety Information according to GHS
Storage class 10 - 13 Other liquids and solids
WGK WGK 1 slightly water endangering
Disposal 3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Storage and Shipping Information
Storage Store at +5°C to +30°C.
Transport Information
Declaration (railroad and road) ADR, RID Kein Gefahrgut
Declaration (transport by air) IATA-DGR No Dangerous Good
Declaration (transport by sea) IMDG-Code No Dangerous Good
Specifications
Assay (Perchloric acid titration, calc. on anhydrous substance (Ph. Eur.)) 99.0 - 101.0 %
Assay (perchloric acid titration, calc. on dried substance (USP)) 99.0 - 100.5 %
Assay (Perchloric acid titration, previously dried substance (JP)) 99.0 - 101.0 %
Identity (Na) passes test
Identity (Citrate) passes test
Identity (reaction upon ignition) passes test
Appearance white to almost white crystals
Appearance of solution (100 g/l, CO₂-free water) clear and colorless
Acidity or alkalinity passes test
pH (50 g/l CO₂-free water) 7.5 - 8.5
Chloride (Cl) ≤ 50 ppm
Sulphate (SO₄) ≤ 150 ppm
Heavy metals (as Pb) ≤ 5 ppm
Al (Aluminium) ≤ 5 ppm
As (Arsenic) ≤ 1 ppm
Hg (Mercury) ≤ 1 ppm
Pb (Lead) ≤ 1 ppm
Oxalate (as C₂H₂O₄) ≤ 100 ppm
Tartrate (C₄H₄O₆) passes test
Residual solvents (Ph. Eur./USP/ICH) excluded by manufacturing process
Readily carbonisable substance passes test
Water (according to Karl Fischer) 11.0 - 13.0 %
Loss on drying (180 °C, 18 h) 10.0 - 13.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, JP, USP, E 331
Conforms to the purity criteria on food additives according to the current European Commission Regulation.
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MERCK 106432 tri-Sodium citrate dihydrate cryst., EMPROVE® ESSENTIAL Ph Eur,BP,JP,USP,E 331

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